Temporal Trends in Hospitalization for Acute Myocardial Infarction Between 2004 and 2011 in Kumamoto, Japan
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Key result
The age-adjusted incidence of acute myocardial infarction in men significantly decreased from 93.1 per 100,000 person-years in 2004 to 70.7 in 2011, while in-hospital cardiac mortality remained low.
Population
8,131 AMI patients hospitalized between 2004 and 2011 in the Kumamoto Prefecture, Japan.
Design
Cohort
Follow-up
in-hospital
Authors
Discussion
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Member takes
Implication
May reflect effective prevention in Japanese men; leaves open generalizability and causal drivers.
Study Design
Type
Observational (n=8,131)
Multicenter
Yes
Structured PICO
P
Population
8,131 patients hospitalized for acute myocardial infarction between 2004 and 2011 in Kumamoto Prefecture, Japan.
O
Outcome
Trends in age-adjusted incidence, age-adjusted in-hospital mortality, and cardiac and noncardiac death rateshard clinical
Main Result
Absolute Event Rate: 70.7% vs 93.1%
p-value: p=0.0294
A steady trend of decreasing AMI incidence was observed in Kumamoto, Japan between 2004 and 2011, while in-hospital cardiac mortality remained stable at approximately 7%.
Limitations
- ST-segment change in the acute phase of MI was not investigated.
- The changing definition of AMI has possibly affected the number of MI diagnoses, with an increase in micro-infarct detection.
- ST-segment change in the acute phase of MI was not investigated
- The changing definition of AMI has possibly affected the number of MI diagnoses, with an increase in micro-infarct detection
Cite This Study
Kojima et al. (2013) conducted an observational in Acute myocardial infarction (n=8,131). Temporal trends (2004-2011) vs. 2004 baseline was evaluated on Age-adjusted AMI incidence per 100,000 person-years in men (p=0.0294). The age-adjusted incidence of acute myocardial infarction in men significantly decreased from 93.1 per 100,000 person-years in 2004 to 70.7 in 2011, while in-hospital cardiac mortality remained low.
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