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January 1, 2021Annals of MedicineOpen Access

Epidemiological trends in mortality, event rates and case fatality of acute myocardial infarction from 2004 to 2015: results from the KORA MI registry

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Key result

Elderly AMI mortality declines up to ~10% annually, with no trend in younger patients.

Why the study?

Epidemiological trends in acute myocardial infarction across different age groups in Germany needed examination.

Population

Registered AMI cases and coronary heart disease deaths in individuals aged 25-84 years in Germany

Comparison

Trends across age groups and sexes from 2004 to 2015

Design

Population-based registry study

Follow-up

28 days

Authors

CKChristina KrämerZimmer Biomet (Netherlands)CMChrista MeisingerUniversity of North Carolina at Chapel HillIKInge KirchbergerUniversity of Augsburg

Discussion

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Member takes

Overview

Mortality declines in elderly AMI patients may reflect care advances; leaves open why younger adults show no improvement.

Study Design

Type

Observational

Structured PICO

P
Population
Population-based KORA myocardial infarction registry cases of AMI and coronary heart disease deaths in 25-74-year-olds from 2004-2015 and 75-84-year-olds from 2009-2015 in Germany.
O
Outcome
Annual age-standardised, age-group- and sex-specific mortality and event rates (incident and recurrent) per 100,000 population as well as 28-day case fatalityhard clinical

AMI mortality and event rates have significantly declined in older populations (75-84 years) in Germany, but these improvements are not seen in younger populations (<55 years).

Cite This Study

Krämer et al. (2021) conducted an observational in Acute myocardial infarction. AMI mortality declined significantly among the elderly (75-84 years) from 2004 to 2015, dropping by 6.0% annually in men and 10.0% in women, with no significant trend in those <55 years.

synapsesocial.com/papers/6a1012085725bbd5cc6077a3https://doi.org/10.1080/07853890.2021.2002926
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