Key result
Pediatric patients infected with enterovirus D68 had twice the odds of presenting with asthma compared to those infected with non-D68 enteroviruses (OR 2.0), though confidence intervals were wide.
Observational (n=210)
Yes
Odds Ratio: 2 (95% CI 0.7–5.8)
Absolute Event Rate: 30.6% vs 18.2%
May inform pediatric respiratory diagnostics; hypothesis-generating and leaves open need for prospective confirmation.
In the late summer and fall of 2014, the province of Alberta, Canada (4.1 million people), was in the midst of peak entero-rhinovirus (ERV) activity, as descriptions of enterovirus D68 (EV-D68) activity were being publicized ([1][1], [2][2]). This analysis was undertaken with several goals: (i) to
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Drews et al. (2015) conducted an observational in Enterovirus/rhinovirus respiratory infection (n=210). Enterovirus D68 (EV-D68) infection vs. Non-D68 enterovirus infection was evaluated on Presentation with asthma (OR 2.0, 95% CI 0.7-5.8). Pediatric patients infected with enterovirus D68 had twice the odds of presenting with asthma compared to those infected with non-D68 enteroviruses (OR 2.0), though confidence intervals were wide.
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