Key result
General fatigue and increasing cognitive load provided no evidence of affecting cognitive functioning in patients with post-polio syndrome.
Why the study?
Does general fatigue or cognitive load affect cognitive functioning in patients with post-polio syndrome?
Observational (n=20)
Does general fatigue or cognitive load affect cognitive functioning in patients with post-polio syndrome?
General fatigue and cognitive load do not appear to significantly impair cognitive functioning in patients with post-polio syndrome.
OBJECTIVE AND DESIGN: This study examined 2 main hypotheses. First, whether patients with post-polio suffering from general fatigue (n=10) demonstrate cognitive deficits compared with patients with post-polio without general fatigue (n=10). Secondly, by systematically varied test order administration we examined whether such differences varied as a function of increasing cognitive load during cognitive testing. SUBJECTS: Twenty patients diagnosed with post-polio syndrome, 10 with general fatigue and 10 without fatigue. RESULTS: Neither of the 2 hypotheses were confirmed. The group with general fatigue reported elevated levels of depression. However, no systematic association between level of depression and cognitive performance could be detected. CONCLUSION: The results of this study provide no evidence that general fatigue or cognitive load affects cognitive functioning in post-polio.
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Östlund et al. (2005) conducted an observational in Post-polio syndrome (n=20). General fatigue vs. No general fatigue was evaluated on Cognitive deficits. General fatigue and increasing cognitive load provided no evidence of affecting cognitive functioning in patients with post-polio syndrome.
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