Key result
Fatigue-related cognitions in severely fatigued patients with post-polio syndrome were not significantly different from those in patients with facioscapulohumeral dystrophy (p > 0.18).
Why the study?
Are fatigue-related cognitions different between severely fatigued patients with post-polio syndrome and facioscapulohumeral dystrophy?
Cross-Sectional (n=45)
Yes
Are fatigue-related cognitions different between severely fatigued patients with post-polio syndrome and facioscapulohumeral dystrophy?
p-value: p=>0.18
Fatigue-related cognitions in severely fatigued patients with post-polio syndrome are not clearly different from those in facioscapulohumeral dystrophy, suggesting the lack of CBT efficacy in PPS is not due to unique cognitive characteristics.
Fatigue cognitions appear similar in PPS and FSHD; leaves open alternative explanations for CBT inefficacy in PPS.
BACKGROUND: Cognitive behavioural therapy does not reduce fatigue in post-polio syndrome, but is effective in facioscapulohumeral dystrophy. This difference in efficacy might be explained by a different role of cognitions in these conditions. OBJECTIVE: To compare fatigue-related cognitions between patients with post-polio syndrome and facio-scapulohumeral dystrophy. SUBJECTS: Patients with post-polio syndrome (n = 21) and facioscapulohumeral dystrophy (n = 24) allocated to a cognitive behavioural therapy intervention in 2 identical trials. METHODS: Assessed cognitions included: sense of control over fatigue; catastrophizing; acceptance; focusing on fatigue; and perceived social support. Group differences in cognitions (independent t-tests or Mann-Whitney U tests) and group differences in the association of cognitions with fatigue (linear regression models) were studied. RESULTS: No differences in cognitions were found between the 2 groups (p > 0.18). Furthermore, there were no cognition-by-group interaction effects, except for "perceived social support", for which a different association with fatigue was found between the 2 groups (p = 0.01). However, univariate models revealed no associations per group. CONCLUSION: Fatigue-related cognitions in severely fatigued patients with post-polio syndrome are not clearly different from that in facioscapulohumeral dystrophy. Thus, the lack of efficacy of cognitive behavioural therapy in post-polio syndrome cannot be attributed to unique cognitive characteristics of this population.
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Koopman et al. (2017) conducted a cross-sectional in Post-polio syndrome and facioscapulohumeral dystrophy with severe fatigue (n=45). Post-polio syndrome vs. Facioscapulohumeral dystrophy was evaluated on Differences in fatigue-related cognitions (sense of control, catastrophizing, acceptance, focusing on fatigue, perceived social support) (p=>0.18). Fatigue-related cognitions in severely fatigued patients with post-polio syndrome were not significantly different from those in patients with facioscapulohumeral dystrophy (p > 0.18).
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