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isomers. Moreover, we determined the X-ray crystal structure of the LecB-photofucose-2 complex, offering insights into its binding mechanism. These findings lay the groundwork for the rational, structure-based design of novel light-responsive compounds targeting LecB and represent a potential new avenue in the development of innovative strategies to combat bacterial resistance.
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Bhattacharya et al. (2025) studied this question.
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