Key result
Foot-and-mouth disease is a highly contagious viral infection causing severe economic losses that is difficult to control due to its complex epidemiology and lack of cross-immunity between strains.
Why the study?
Foot-and-mouth disease is a highly contagious viral disease that primarily affects animals with cloven hooves and is difficult to control due to its complex epidemiological nature and poor diagnostic facilities.
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This review summarizes the epidemiology, diagnostic techniques, and control strategies for foot-and-mouth disease, highlighting the need for multivalent vaccines and better diagnostic capabilities.
Foot-and-mouth disease (FMD) is a viral disease that primarily affects animals with cloven hooves. It is a highly contagious disease and difficult to control due to its complex epidemiological nature and poor diagnostic facilities. Thus, this paper aimed to review the epidemiology of FMD, and its economic impact on farmers, discuss the available diagnostic, and prevention and control methods that can be practiced. Foot-and-mouth disease virus (FMDV) is the causative agent of FMD, and it is a single-stranded RNA virus with a positive sense that belongs to the genus Aphthovirus and the family Picornaviridae. The virus has seven serologically and genetically distinct serotypes, namely O, A, C, Asia1, SAT1, SAT2, and SAT3, as well as over 60 subtypes. The virus is inactivated by heat, UV radiation, pH levels below 6.5 or above 9, gamma irradiation, chemicals, and disinfectants, but it is almost indefinitely stable at temperatures below freezing point. The tongue, dental pad, gums, cheek, hard and soft palates, lips, nostrils, muzzle, interdigital space (between the hooves), and a coronary band of affected animals develop vesicular lesions. Viruses can be spread orally or via the respiratory tract. FMD is diagnosed based on clinical signs, and using epidemiological methods and laboratory techniques. FMD causes severe economic losses as a result of high morbidity associated with outbreak occurrences, limiting the introduction of improved production technologies in the area, restrictions on international trade, and costs associated with the application of control measures. Some of the control and prevention methods for FMD are vaccination, animal movement control, physical separation from wildlife, and symptomatic treatment. But due to its complex epidemiological nature, limited diagnostic capabilities, and no cross-immunity between strains, FMD was difficult to control. Therefore, awareness creation among animal owners about the disease, and possible prevention and control methods that can be practiced is required. And also, research in the development of a multivalent and protective vaccine is recommended.
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Yirdaw et al. (2023) conducted a review in Foot-and-Mouth Disease. Foot-and-mouth disease is a highly contagious viral infection causing severe economic losses that is difficult to control due to its complex epidemiology and lack of cross-immunity between strains.
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