Measuring the effects of exercise in neuromuscular disorders: a systematic review and meta-analyses

Figures

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  Figure 1.. Flow chart of study selection.

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  Figure 2.. VO 2peak (ml/kg/min) (exercise training versus usual care). Random-effects meta-analysis of exercise-trained (Ex) compared to usual care (UC) on VO 2peak (ml/kg/min); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; green, combined training.

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  Figure 3.. Peak power (watts) (exercise training versus usual care). Random-effects meta-analysis of exercise-trained (Ex) compared to usual care (UC) on peak power (watts); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; green, combined training.

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  Figure 4.. VO 2peak (ml/kg/min) (before versus after exercise training). Random-effects meta-analysis of exercise training on VO 2peak (ml/kg/min); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training; green, combined training.*mitochondrial myopathies; **McArdle’s disease; ‡non-mitochondrial myopathies; §hospital-based training; §§home-based training.

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  Figure 5.. Peak power (watts) (before versus after exercise training). Random-effects meta-analysis of exercise training on Peak Power (watts); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training; green, combined training.* mitochondrial myopathies; ** McArdle’s disease.

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  Figure 6.. 6MWT (metres) (before versus after exercise training). Random-effects meta-analysis of exercise training on 6MWT (metres); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training; green, combined training.

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  Figure 7.. Sit-to-stand (STS) (repetitions) (before versus after exercise training). Random-effects meta-analysis of exercise training on STS (repetitions); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training; green, combined training.

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  Figure 8.. Sit-to-stand (STS) (seconds) (before versus after exercise training). Random-effects meta-analysis of exercise training on STS (seconds); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training.

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  Figure 9.. Rise from supine (seconds) (before versus after exercise training). Random-effects meta-analysis of exercise training on Rise from supine (seconds); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training; green, combined training.

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  Figure 10.. SF-36 (before versus after exercise training). Random-effects meta-analysis of exercise training on Short Form 36 health survey (SF-36); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training. ‡non-mitochondrial myopathies; *mitochondrial myopathies.

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  Figure 11.. Fatigue severity scale (before versus after exercise training). Random-effects meta-analysis of exercise training on fatigue severity scale (FSS); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training; green, combined training. §hospital-based training; §§home-based training.

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  Figure 12.. Central nuclei (%) (before versus after exercise training). Random-effects meta-analysis of exercise training on central nuclei (%); pooled analysis of all trials using the final training intervention time point. Red denotes aerobic training; blue, strength training.