Key result
Post-poliomyelitis syndrome was associated with a 27% lower mean maximal voluntary ventilation compared with healthy controls (p=0.0127), though values remained within normal limits.
Why the study?
Does post-poliomyelitis syndrome impair lung function compared to healthy controls or patients with poliomyelitis sequelae without the syndrome?
Cross-Sectional (n=29)
Does post-poliomyelitis syndrome impair lung function compared to healthy controls or patients with poliomyelitis sequelae without the syndrome?
p-value: p=0.0127
Outpatients with post-poliomyelitis syndrome have preserved lung function and respiratory muscle strength comparable to healthy controls and those with poliomyelitis sequelae.
Post-poliomyelitis syndrome outpatients show preserved lung function; leaves open whether subtle ventilatory differences merit longitudinal monitoring.
OBJECTIVE: To compare lung function between patients with post-poliomyelitis syndrome and those with sequelae of paralytic poliomyelitis (without any signs or symptoms of post-poliomyelitis syndrome), as well as between patients with post-poliomyelitis syndrome and healthy controls. METHODS: Twenty-nine male participants were assigned to one of three groups: control; poliomyelitis (comprising patients who had had paralytic poliomyelitis but had not developed post-poliomyelitis syndrome); and post-poliomyelitis syndrome. Volunteers underwent lung function measurements (spirometry and respiratory muscle strength assessment). RESULTS: The results of the spirometric assessment revealed no significant differences among the groups except for an approximately 27% lower mean maximal voluntary ventilation in the post-poliomyelitis syndrome group when compared with the control group (p = 0.0127). Nevertheless, the maximal voluntary ventilation values for the post-poliomyelitis group were compared with those for the Brazilian population and were found to be normal. No significant differences were observed in respiratory muscle strength among the groups. CONCLUSIONS: With the exception of lower maximal voluntary ventilation, there was no significant lung function impairment in outpatients diagnosed with post-poliomyelitis syndrome when compared with healthy subjects and with patients with sequelae of poliomyelitis without post-poliomyelitis syndrome. This is an important clinical finding because it shows that patients with post-poliomyelitis syndrome can have preserved lung function.
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Lira et al. (2013) conducted a cross-sectional in post-poliomyelitis syndrome (n=29). Post-poliomyelitis syndrome vs. Sequelae of paralytic poliomyelitis without post-poliomyelitis syndrome, and healthy controls was evaluated on Lung function (spirometry and respiratory muscle strength) (p=0.0127). Post-poliomyelitis syndrome was associated with a 27% lower mean maximal voluntary ventilation compared with healthy controls (p=0.0127), though values remained within normal limits.
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