Key result
In patients with sick sinus syndrome treated with AAI/AAIR pacing, AV block requiring implantation of a ventricular lead occurred at an annual rate of 1.7%.
Why the study?
Does AAI/AAIR pacemaker implantation result in a low incidence of AV block requiring a ventricular lead in patients with sick sinus syndrome?
Observational (n=399)
No
Does AAI/AAIR pacemaker implantation result in a low incidence of AV block requiring a ventricular lead in patients with sick sinus syndrome?
In patients with sick sinus syndrome, AAI/AAIR pacing is associated with a low annual incidence (1.7%) of developing AV block requiring a ventricular lead, supporting its safety and reliability.
Answers are grounded in this paper and cite their sources.
AAI/AAIR pacing was associated with low AV block rates in sick sinus syndrome; leaves open randomized confirmation before broader adoption.
This retrospective study included a large cohort of consecutive patients primarily implanted at Skejby University Hospital with an AAI/AAIR pacemaker because of sick sinus syndrome (SSS) from July 1981 to July 1999. The primary aim of the study was to analyze the risk of developing AV block during long-term follow-up. A secondary aim was to study the incidence and reasons for changes in pacing mode caused by other than AV block. A total of 399 patients (231 women, mean age 71 +/- 13.5 years) were identified. Mean follow-up was 4.6 +/- 3.4 years and occurred at death, reoperation with mode change, pacemaker explant, or end of study. During follow-up, 44 patients had a ventricular lead implanted with a mean delay of 2.8 +/- 3.1 years (range 1 day-10.4 years) after the primary implantation. A total of 30 patients received a ventricular lead because of AV block or AF with bradycardia (annual incidence 1.7%). Another 14 patients received a ventricular lead without having documented AV block or AF with pauses (annual incidence 0.8%). The present observational study documents that in patients with SSS treated with AAI/AAIR pacing, AV block requiring implantation of a ventricular lead occurs at a rate of 1.7% per year. It is considered that AAI/AAIR pacing is safe and reliable as treatment for patients with SSS and normal AV conduction.
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Kristensen et al. (2001) conducted an observational in Sick sinus syndrome (SSS) (n=399). AAI/AAIR pacemaker was evaluated on AV block requiring implantation of a ventricular lead. In patients with sick sinus syndrome treated with AAI/AAIR pacing, AV block requiring implantation of a ventricular lead occurred at an annual rate of 1.7%.
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