Key result
Second-trimester ultrasound screening detected 65.7% (95% CI 57.8-74.7) of major congenital heart defects overall, with systematic examination and specialist availability predicting higher detection.
Population
1,060 major congenital heart defects from 33 hospitals providing complete data for a national survey in Spain.
Design
Cross-sectional
Authors
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Supports specialist fetal echocardiography availability; leaves open whether systematic screening improves outcomes in routine practice.
Cross-Sectional (n=1,060)
Yes
Routine second-trimester ultrasound screening detects approximately half of major congenital heart defects, with detection rates improved by systematic examination and availability of fetal echocardiography specialists.
Galindo et al. (2010) conducted a cross-sectional in Congenital heart defects (n=1,060). Second-trimester ultrasound screening was evaluated on Overall prenatal detection rate of major CHD (95% CI 57.8-74.7). Second-trimester ultrasound screening detected 65.7% (95% CI 57.8-74.7) of major congenital heart defects overall, with systematic examination and specialist availability predicting higher detection.
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