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Because of great species variation in the effects of neuromuscular blocking agents, the results are often not applicable to man. Although the subject has been very extensively studied in experimental animals, the necessity has been pointed out for determining the actions of these drugs in man as well. Symposia have been held and monographs written, but this is the first attempt to review the entire literature of the pharmacology of the muscle relaxants in man.
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Francis F. Foldes (1960) studied this question.