Key result
Coarctation of the aorta represents a complex vasculopathy associated with variable arch anatomy, left-sided heart lesions, and significant risk of hypertension and early morbidity.
Coarctation of the aorta should be viewed as a complex, systemic vasculopathy requiring lifelong evaluation and management rather than a simple, curable discrete narrowing.
Supports lifelong surveillance in coarctation; leaves open optimal strategies for associated systemic vasculopathy.
Coarctation of the aorta was once viewed as a simple discrete narrowing of the aortic isthmus that could be 'cured' by surgical intervention. It is now clear that this condition may: (1) affect the aortic arch in a highly variable manner; (2) be associated with a host of other left sided heart lesions; (3) represent a wider vasculopathy within the pre-coarctation arterial tree, leading to significant prevalence of hypertension by adolescence, and subsequent risk of early morbidity and death. This review outlines the evaluation and treatment of this disease from pre-natal to adult life.
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Kenny et al. (2011) conducted a review in Coarctation of the aorta. Coarctation of the aorta represents a complex vasculopathy associated with variable arch anatomy, left-sided heart lesions, and significant risk of hypertension and early morbidity.
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