Key result
Microparticles act as biomarkers of vascular injury and inflammation, contributing to the initiation and development of atherosclerosis and offering potential prognostic value in cardiovascular diseases.
Microparticles are emerging as potential biomarkers and prognostic tools for assessing vascular health and atherosclerosis.
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Hypothesis-generating for microparticle biomarkers in atherosclerosis; prospective validation required before clinical adoption.
Microparticles (MPs) are membrane vesicles released by various cell types (platelets, endothelial cells, monocytes) in circulation, which play inevitable role in thrombosis and vascular inflammation. Literatures so far suggested MPs as biomarkers of vascular injury and inflammation and also contribute to the initiation and development of atherosclerosis and its related manifestations. Atherosclerosis is the major underlying pathophysiology for the various cardio vascular diseases (CVDs). In addition, most recent data suggest a potential prognostic role of circulating MPs. Present article summarizes briefly about the different MPs and their importance as markers to check the vascular health in various CVDs.
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A 2014 study conducted a review in Atherosclerosis and Cardiovascular Diseases. Microparticles was evaluated. Microparticles act as biomarkers of vascular injury and inflammation, contributing to the initiation and development of atherosclerosis and offering potential prognostic value in cardiovascular diseases.
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