Key result
Body composition influenced stress-induced pressure natriuresis, with total percent body fat accounting for 11.2% of the variance in stress urinary sodium excretion.
Why the study?
Does body composition influence stress-induced pressure natriuresis in youth?
Observational (n=127)
Does body composition influence stress-induced pressure natriuresis in youth?
p-value: p=.001
In youths, lean body mass predicts stress-induced blood pressure increases, while fat mass inversely correlates with stress-induced sodium excretion.
May link adiposity to stress natriuresis in youth; hypothesis-generating and should not change practice.
BACKGROUND: The contribution of stress to obesity-related cardiovascular disease is uncertain. The purpose of this study was to examine the influence of body composition on stress-induced pressure natriuresis. METHODS: Dual energy x-ray absorptiometry was performed in 127 African American and white youths to assess lean body mass (LBM), fat mass (FM), and total percentage of body fat (%BF). The stress protocol was comprised of a 2-h baseline period, 1-h video game competition stressor, and 2-h recovery period. Blood and urine samples were collected hourly and blood pressure (BP) was obtained at 15-min intervals. RESULTS: Both BP and urinary sodium excretion(U(Na)V) increased from baseline to stress and returned to prestress levels after stress (P = .001 for each). The BP levels and changes were positively correlated with LBM. In contrast, levels and changes in sodium excretion U(Na)V were inversely correlated with FM and %BM. Multiple regression analyses that included ethnicity, sex, angiotensin II (Ang II), and measures of body composition in the models indicated the following: a) LBM was the best predictor of stress systolic BP and independently contributed with ethnicity to stress diastolic BP; b) ethnicity was the only independent predictor of the stress-related change in systolic and diastolic BP; c) LBM was the only independent predictor of the change in BP from stress to recovery for both systolic and diastolic BP; and d) total percent body fat accounted for 11.2% of the variance of stress U(Na)V, with Ang II contributing an additional 6.1%. CONCLUSIONS: Based on the results of this study, ethnicity and body composition are related to stress-induced pressure natriuresis.
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Wilson et al. (2004) reported an observational. Body composition (lean body mass, fat mass, percent body fat) was evaluated on Changes in blood pressure and urinary sodium excretion from baseline to stress (p=.001). Body composition influenced stress-induced pressure natriuresis, with total percent body fat accounting for 11.2% of the variance in stress urinary sodium excretion.