Key result
Kindergarten attendance was associated with a high EV-D68 seroconversion rate of 73% among initially seronegative children, indicating high susceptibility to infection.
Why the study?
Enterovirus D68 is an emerging disease affecting mostly children, but few investigations have clarified its transmission and seroprevalence within daycares and kindergartens.
Population
190 kindergarten attendees aged between two to five years old in Taipei City, Taiwan
Design
Prospective cohort study
Authors
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High seroconversion suggests underestimated EV-D68 burden in preschoolers; leaves open targeted prevention trials.
Cohort (n=190)
No
Preschool-aged children are highly susceptible to EV-D68 infection, indicating that the disease burden may be underestimated and highlighting the need for preventive measures in daycares.
Hu et al. (2019) conducted a cohort in Enterovirus D68 infection (n=190). Kindergarten attendance (EV-D68 exposure) was evaluated on EV-D68 seroconversion rate. Kindergarten attendance was associated with a high EV-D68 seroconversion rate of 73% among initially seronegative children, indicating high susceptibility to infection.
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