Key result
A new theoretical simulation of the nonlinear response of a microvascular segment to a pressure step permitted indirect determination of vessel compliance, agreeing with previous studies.
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A new theoretical approach allows for the indirect determination of microvascular compliance by analyzing the nonlinear response to a pressure step.
A new theoretical approach was used to study the nonlinear response of a microvascular segment subjected to a pressure step at one end. The method is suitable for both large and small deformations of the vessel wall in the case of an elastic response of the segment. It is shown that the use of this simulation permits an indirect determination of the compliance of the vessel. The procedure is applied in two cases of major interest: first the in-vivo study of the intermittent blood flow in the microcirculation, and second, the analysis of experiments using micropipettes. The resulting values of the compliance agree with other values found in the previous studies. The theoretical method is particularly adapted to nonlinear equations.
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Guiffant et al. (1998) studied Intermittent blood flows in microcirculation. Theoretical simulation of nonlinear response to a pressure step was evaluated on Indirect determination of vessel compliance. A new theoretical simulation of the nonlinear response of a microvascular segment to a pressure step permitted indirect determination of vessel compliance, agreeing with previous studies.
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