Why the study?
Can massive doses of procainamide safely prevent malignant ventricular arrhythmias in patients with reinfarction?
Can massive doses of procainamide safely prevent malignant ventricular arrhythmias in patients with reinfarction?
Massive doses of intravenous procainamide may be necessary and tolerated without side effects to suppress malignant ventricular arrhythmias following reinfarction.
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May support high-dose procainamide in refractory post-MI arrhythmias; single case report leaves open need for controlled safety trials.
Mattiasson et al. (1978) studied this question.
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