Key result
Plasmapheresis resulted in a rapid mean reduction of serum triglycerides by 73.53% after the first session in patients with hypertriglyceride-induced acute pancreatitis.
Why the study?
Hypertriglyceride-induced acute pancreatitis is a devastating condition where rapid reduction of serum triglycerides is a key factor in management.
Does plasmapheresis reduce serum triglyceride levels in patients with hypertriglyceride-induced acute pancreatitis?
Case Report (n=4)
No
Does plasmapheresis reduce serum triglyceride levels in patients with hypertriglyceride-induced acute pancreatitis?
Plasmapheresis is a safe and effective therapeutic option for the rapid reduction of serum triglycerides in patients with hypertriglyceride-induced acute pancreatitis.
May support plasmapheresis for rapid triglyceride reduction in hypertriglyceridemia-induced pancreatitis; leaves open confirmation in randomized trials.
Hypertriglyceride-induced Acute Pancreatitis is a devasting condition. The rapid reduction of serum triglyceride is a key factor in its management. Beside the reduction in Triglyceride level plasmapheresis has other added advantage. Early initiation of plasmapheresis within 48 hrs has a better outcome. Plasmapheresis should be performed until triglyceride levels have been lowered to 500mg/dl. Here, we present a series of four cases of hypertriglyceride induced pancreatitis who underwent plasmapheresis. All the patients were diabetics. All cases showed the rapid reduction of triglyceride levels after plasmapheresis. Three patients were discharge from hospital, where as one patient died due to Sepsis. Out of four patients only one required Renal Replacement therapy.
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Chowdhary et al. (2020) conducted a case report in Hypertriglyceride-induced acute pancreatitis (n=4). Plasmapheresis was evaluated on Mean percentage decrease in triglyceride level after the first session. Plasmapheresis resulted in a rapid mean reduction of serum triglycerides by 73.53% after the first session in patients with hypertriglyceride-induced acute pancreatitis.
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