Plasma Cell Myeloma

Article1 May 1953PLASMA CELL MYELOMAGORDON C. MEACHAM, M.D.GORDON C. MEACHAM, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-5-1035 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONPlasma cell myeloma is a well known disease often associated with obvious clinical and pathologic findings. However, in a study of 51 patients with this disease at the University Hospitals of Cleveland since 1933, it was apparent that certain aspects of the disease have not been sufficiently recognized. In particular, the type of anemia, the character of radiologic changes in the bones, sternal marrow findings and certain metabolic disturbances, if recognized as being part of the disease, may permit an earlier diagnosis than would otherwise be the case. Abnormal hematologic, orthopedic, metabolic and renal manifestations may occur during the...Bibliography1. Wintrobe MM: Clinical hematology, 1951, Lea and Febiger, Philadelphia. Google Scholar2. AdamsAllingLawrence WSELJS: Multiple myeloma, Am. J. Med. 6: 141, 1949. CrossrefMedlineGoogle Scholar3. JacksonParker HF: Hodgkin's disease and allied disorders, 1947, Oxford University Press, New York. Google Scholar4. FademMcBirnie RSJE: Plasmacytosis in diseases other than primary plasmacytic disease, Blood 5: 191, 1950. CrossrefMedlineGoogle Scholar5. StewartWeber AFP: Myelomatosis, Quart. J. Med. 7: 211, 1938. Google Scholar6. Bing J: Further investigations on hyperglobulinemia. II. Is serum globulin formed from plasma cells and reticulo-endothelial cells? Acta. med. Scandinav. 103: 565, 1940. CrossrefGoogle Scholar7. Albright F: The parathyroid glands and metabolic bone disease, 1948, Williams and Wilkins Co., Baltimore. Google Scholar8. BayrdHeck EDFJ: Multiple myeloma—a review of 83 proven cases, J. A. M. A. 133: 147, 1947. CrossrefMedlineGoogle Scholar9. MorisetteWatkins LCH: Multiple myeloma, Proc. Staff Meet., Mayo Clin. 17: 433, 1942. Google Scholar10. Fishberg AM: Hypertension and nephritis, 1944, Lea and Febiger, Philadelphia. Google Scholar11. Duncan G: Diseases of metabolism, 1951, W. B. Saunders Co., Philadelphia. Google Scholar12. Miller M: The diffusible calcium of serum and transudates in vivo, J. Biol. Chem. 122: 71, 1937. CrossrefGoogle Scholar13. LogeRundles JPRW: Methane (ethyl carbamate) therapy in multiple myeloma, Blood 4: 201, 1949. CrossrefMedlineGoogle Scholar14. ThornForshamFrawleyHillRocheStachelinWilson GWPHTFSRMDDL: The clinical usefulness of ACTH and cortisone, New England J. Med. 242: 783, 1950. CrossrefMedlineGoogle Scholar15. DameshekRosenthalSchwartz WMCLI: The treatment of acquired hemolytic anemia with adrenocorticotrophic hormone (ACTH), New England J. Med. 244: 117, 1951. CrossrefGoogle Scholar16. BlackmanBarkerBuellDavis SSWHMVBD: On the pathogenesis of renal failure associated with multiple myeloma. Electrophoretic and chemical analysis of protein in the urine and blood stream, J. Clin. Investigation 23: 163, 1944. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication January 9, 1953.From the Department of Medicine, Western Reserve University School of Medicine, Cleveland, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPleural Effusion Due to Multiple MyelomaMYELOMATOSIS, A SPECTRUM OF DISEASE: ITS CLINICAL PRESENTATION, DIAGNOSIS AND PROGNOSISREFERENCESMultiple Myeloma Presenting as Pulmonary Infiltration: Report of a CaseMyelomatosisMyelomatosis with Extensive Pulmonary InvolvementULCERATION OF THE SKIN IN MULTIPLE MYELOMA.Multiple myeloma manifested as a problem in the diagnosis of pulmonary diseaseMassive metastatic pulmonary calcinosis in a case of multiple myelomaROENTGENOLOGIC AND CLINICAL ASPECTS OF MULTIPLE MYELOMA WITH REPORT OF AN UNUSUAL CASE*OTTO DEUTSCHBERGER, HERLEY FUJIYLong Survival in Multiple MyelomaMULTIPLE MYELOMA: REPORT OF A CASE SHOWING UNUSUAL REMISSION LASTING TWO YEARS FOLLOWING SEVERE HEPATITIS*ROSE E. LONDON, M.D.Atypical amyloidosis and bone marrow plasmacytosis in a case of hypersensitivity to sulfonamides 1 May 1953Volume 38, Issue 5Page: 1035-1047KeywordsAnemiaBone marrowBone marrow disordersMetabolic disordersMultiple myelomaOrthopedics Issue Published: 1 May 1953 PDF downloadLoading ...