July 15, 1995Cancer

Cutaneous angiosarcoma of the head and neck. A therapeutic dilemma

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Why the study?

Does electron-beam radiation improve local control and survival in patients with cutaneous angiosarcoma of the head and neck?

Population

14 patients with dermal angiosarcoma of the head and neck

Comparison

Electron-beam radiation vs Patients irradiated with clinically evident…

Design

Cohort

Follow-up

5 years (actuarial)

Authors

WMWilliam H. MorrisonThe University of Texas MD Anderson Cancer Center RBRobert M. ByersThe University of Texas MD Anderson Cancer Center AGAdam S. GardenAmerican College of Radiology

Discussion

Member takes

Implication

Clinical disease at irradiation linked to inferior survival; leaves open optimal radiation timing after resection in cutaneous angiosarcoma.

Structured PICO

Does electron-beam radiation improve local control and survival in patients with cutaneous angiosarcoma of the head and neck?

Population

14 patients with dermal angiosarcoma of the head and neck (11 scalp and forehead, 3 upper face; 11 presented with multiple foci of disease)

Intervention

Electron-beam radiation (median 60 Gy over 40 days for post-operative patients; 55-75 Gy over median 44 days for patients with clinically evident disease)

Comparator

Patients irradiated with clinically evident disease versus patients irradiated without clinically detectable disease (post-operative)

Outcome

5-year actuarial control rates above the clavicles and 5-year actuarial survival ratehard clinical

Radiation is an effective modality for treating local disease in cutaneous angiosarcoma of the head and neck, especially when used after surgical resection of macroscopic tumor.

Cite This Study

Morrison et al. (1995) studied this question.

synapsesocial.com/papers/6a94ebeea9fda6dc960f30d6 https://doi.org/10.1002/1097-0142(19950715)76:2<319::aid-cncr2820760224>3.0.co;2-8

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Implication

Clinical disease at irradiation linked to inferior survival; leaves open optimal radiation timing after resection in cutaneous angiosarcoma.

Cutaneous angiosarcoma of the head and neck. A therapeutic dilemma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Cutaneous angiosarcoma of the head and neck. A therapeutic dilemma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider