The familial occurrence of berry aneurysm.

'that there may be a familial factor in the occurrence of intracerebral aneurysm is a possibility that has not been advanced, to the knowledge of the authors'. However, O'Brien in 1942 had reported a case of middle cerebral aneurysm in a man whose twin brother had died eight years previously under conditions strongly suggestive of subarachnoid haemorrhage. A similar pair of identical twins was described by Jokl and Wolffe (1954). Since 1954 several reports of intracranial aneurysm in more than one member of a family have been published. The purpose of this paper is to present a family in which three members have had congenital intra-cranial vascular lesions. The case histories and re-levant radiological findings of three sisters will be