What question did this study set out to answer?

To evaluate whether a recruitment manoeuvre restores end-expiratory lung volume to baseline in children undergoing general anaesthesia with a supraglottic airway using electrical impedance tomography.

September 24, 2025British Journal of AnaesthesiaOpen Access

Efficacy of a lung recruitment manoeuvre in children undergoing general anaesthesia with a supraglottic airway

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Authors

RLRicarda Lippuner CPCharlotte Pellaud MHMarkus Huber

Discussion

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Overview

Clinical trial reveals a lung recruitment manoeuvre restores baseline end-expiratory lung volume in anaesthetised children using a supraglottic airway, indicating an effective countermeasure to...

Key Points

To evaluate whether a recruitment manoeuvre restores end-expiratory lung volume to baseline in children undergoing general anaesthesia with a supraglottic airway using electrical impedance tomography.
Conducted an interventional trial (NCT05672329) in 95 eligible children (10–20 kg, ASA physical status 1–2) undergoing general anaesthesia with a supraglottic airway, analysing 74 complete datasets.
Administered a recruitment manoeuvre via spontaneous breathing with 3 L min⁻¹ fresh gas flow (FiO₂ 1.0) and an adjustable pressure-limiting valve at 30 cmH₂O until a pressure plateau or leak occurred.
Evaluated electrical impedance tomography at induction baseline, after airway placement, and after the manoeuvre, defining equivalence as a 95% CI of ΔEELV within ±35% (±2 ml kg⁻¹).
The median estimated difference in end-expiratory lung volume between post-recruitment manoeuvre and baseline was −0.9 ml kg⁻¹ (95% CI, −1.6 to −0.1 ml kg⁻¹), meeting the preset equivalence margin.
No significant changes were detected in ventilation distribution homogeneity, with a median global inhomogeneity index change of 0.0 (95% CI, 0.03 to 0.04).

Cite This Study

Lippuner et al. (2025) studied this question.

synapsesocial.com/papers/6a94f27e1fe04514d10f32ea https://doi.org/10.1016/j.bja.2025.08.016

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September 24, 2025British Journal of AnaesthesiaOpen Access

Efficacy of a lung recruitment manoeuvre in children undergoing general anaesthesia with a supraglottic airway

View Full Paper

Ask AI

Bookmark

Authors

RLRicarda Lippuner CPCharlotte Pellaud MHMarkus Huber

Discussion

Member takes

Overview

Clinical trial reveals a lung recruitment manoeuvre restores baseline end-expiratory lung volume in anaesthetised children using a supraglottic airway, indicating an effective countermeasure to...

Key Points

To evaluate whether a recruitment manoeuvre restores end-expiratory lung volume to baseline in children undergoing general anaesthesia with a supraglottic airway using electrical impedance tomography.
Conducted an interventional trial (NCT05672329) in 95 eligible children (10–20 kg, ASA physical status 1–2) undergoing general anaesthesia with a supraglottic airway, analysing 74 complete datasets.
Administered a recruitment manoeuvre via spontaneous breathing with 3 L min⁻¹ fresh gas flow (FiO₂ 1.0) and an adjustable pressure-limiting valve at 30 cmH₂O until a pressure plateau or leak occurred.
Evaluated electrical impedance tomography at induction baseline, after airway placement, and after the manoeuvre, defining equivalence as a 95% CI of ΔEELV within ±35% (±2 ml kg⁻¹).
The median estimated difference in end-expiratory lung volume between post-recruitment manoeuvre and baseline was −0.9 ml kg⁻¹ (95% CI, −1.6 to −0.1 ml kg⁻¹), meeting the preset equivalence margin.
No significant changes were detected in ventilation distribution homogeneity, with a median global inhomogeneity index change of 0.0 (95% CI, 0.03 to 0.04).

Cite This Study

Lippuner et al. (2025) studied this question.

synapsesocial.com/papers/6a94f27e1fe04514d10f32ea https://doi.org/10.1016/j.bja.2025.08.016

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