Key result
Native aortic root thrombosis can occur late after the Fontan procedure in patients with hypoplastic left heart syndrome, leading to life-threatening coronary embolization and myocardial infarction.
Why the study?
Patients with single ventricle physiology post-Fontan procedure are at risk for life-threatening thrombus formation in the native aortic root, but optimal prevention and treatment strategies remain poorly defined.
Case Report (n=3)
No
Highlights a rare but life-threatening complication of native aortic root thrombosis leading to myocardial infarction in patients with single ventricle physiology late after the Fontan procedure.
Answers are grounded in this paper and cite their sources.
Heightens vigilance for NAR thrombus in Fontan patients; case series leaves optimal prevention open.
Patients with single ventricle physiology who have undergone the Fontan procedure are at risk for long-term complications such as thrombus formation. Thrombus formation in the native aortic root (NAR) can be life-threatening if retrograde filling of the coronary arteries (CAs) is impaired. We present three cases of NAR thrombus with embolization to the CA, resulting in myocardial infarction. Thromboembolic events are well-documented complications of Fontan physiology, and optimal prevention and treatment strategies are poorly defined.
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Patel et al. (2021) conducted a case report in Hypoplastic left heart syndrome (HLHS) post-Fontan operation (n=3). Native aortic root thrombosis was evaluated on Myocardial infarction and thromboembolic complications. Native aortic root thrombosis can occur late after the Fontan procedure in patients with hypoplastic left heart syndrome, leading to life-threatening coronary embolization and myocardial infarction.
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