Why the study?
Does oral contraceptive medication alter plasma levels of angiotensin II and serum activity of angiotensin I-converting enzyme in healthy young women?
Population
11 healthy, normotensive young women taking contraceptive medication for at least one year, and healthy male…
Comparison
Oral contraceptive medication for at least one… vs Healthy male and female controls
Design
Cross-sectional
Authors
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OC use was associated with higher angiotensin II levels without ACE activity change; hypothesis-generating for vascular risk and requires prospective confirmation.
Does oral contraceptive medication alter plasma levels of angiotensin II and serum activity of angiotensin I-converting enzyme in healthy young women?
Oral contraceptive use increases plasma angiotensin II levels without significantly altering serum angiotensin I-converting enzyme activity.
Zakheim et al. (1976) studied this question.
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