Key result
Platelet accumulation was 4.9+/-0.8 times higher downstream from coil stents compared to tube stents (P<0.01) in an ex vivo flow chamber system.
Effect estimate: 4.9+/-0.8 times more
p-value: p=<0.01
An ex vivo perfusion system can reproduce in vivo stent thrombosis characteristics, demonstrating higher thrombogenicity of coil stents and the efficacy of dual antiplatelet therapy and GP IIb/IIIa inhibitors.
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Coil stents linked to higher downstream platelet accumulation; hypothesis-generating for stent design effects on thrombosis risk, requiring clinical validation.
Sakakibara et al. (2002) studied Stent thrombosis. Coil stents vs. Tube stents was evaluated on Platelet accumulation downstream from stents (4.9+/-0.8 times more, p=<0.01). Platelet accumulation was 4.9+/-0.8 times higher downstream from coil stents compared to tube stents (P<0.01) in an ex vivo flow chamber system.
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