Key result
Infarct border zone entropy was independently associated with primary endpoint events in patients with previous myocardial infarction (HR 3.859; 95% CI 2.136-6.974).
Why the study?
Sudden cardiac death after myocardial infarction is mostly caused by ventricular arrhythmias, with the infarct border zone acting as an arrhythmogenic substrate that leads to adverse electrophysiological properties.
Does the assessment of cardiac-MRI scar entropy combined with left ventricular strain improve prognostication for endpoint events in patients with previous myocardial infarction?
Comparison
Myocardial scar entropy and LV strain parameters in patients with vs without endpoint events
Design
Prospective study
Authors
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May enhance post-MI SCD risk stratification via scar entropy and strain; leaves open prospective validation before clinical use.
Cohort (n=157)
Does the assessment of cardiac-MRI scar entropy combined with left ventricular strain improve prognostication for endpoint events in patients with previous myocardial infarction?
Hazard Ratio: 3.859 (95% CI 2.136–6.974)
Cardiac MRI-derived border zone scar entropy and global longitudinal strain provide incremental prognostic value over LVEF in patients with prior myocardial infarction.
Zhao et al. (2022) conducted a cohort in Myocardial Infarction (n=157). Infarct border zone (BZ) entropy was evaluated on Primary endpoint events (HR 3.859, 95% CI 2.136-6.974). Infarct border zone entropy was independently associated with primary endpoint events in patients with previous myocardial infarction (HR 3.859; 95% CI 2.136-6.974).
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