Key result
A low prognostic nutritional index (≤47.8) was significantly associated with increased hospital mortality compared to a high index (47.4% vs 10.9%; OR 7.329) in patients with acute stroke in the ICU.
Why the study?
The prognostic nutritional index predicts prognosis in conditions like ischemic heart disease and pulmonary embolism, but its association with mortality in acute stroke patients admitted to the ICU required investigation.
Does a low Prognostic Nutritional Index predict mortality and worse clinical outcomes in patients with acute stroke in the ICU?
Cohort (n=102)
No
Does a low Prognostic Nutritional Index predict mortality and worse clinical outcomes in patients with acute stroke in the ICU?
Odds Ratio: 7.329 (95% CI 2.667–20.137)
Absolute Event Rate: 47.4% vs 10.9%
p-value: p=<0.001
A low Prognostic Nutritional Index (≤47.8) is associated with greater disease severity and longer hospital/ICU stays in patients with acute stroke.
Low PNI may flag higher-risk stroke ICU patients; hypothesis-generating for mortality prediction, needs prospective validation before practice change.
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Yeşiler et al. (2022) conducted a cohort in Ischemic and hemorrhagic acute stroke (n=102). Low Prognostic Nutritional Index (PNI ≤ 47.8) vs. High Prognostic Nutritional Index (PNI > 47.8) was evaluated on Mortality (OR 7.329, 95% CI 2.667-20.137, p=<0.001). A low prognostic nutritional index (≤47.8) was significantly associated with increased hospital mortality compared to a high index (47.4% vs 10.9%; OR 7.329) in patients with acute stroke in the ICU.
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