Key result
Patients with heart failure with preserved ejection fraction frequently experience profound limitations in exercise capacity and a blunted heart rate response to exertion.
Why the study?
Does rate-adaptive pacing improve outcomes in patients with heart failure with preserved ejection fraction?
Does rate-adaptive pacing improve outcomes in patients with heart failure with preserved ejection fraction?
This editorial discusses the potential role and limitations of rate-adaptive pacing in patients with heart failure with preserved ejection fraction.
More than 64 million individuals worldwide and more than 6 million patients in the United States have been diagnosed with heart failure (HF).1,2 Heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of HF cases and is anticipated to be the most common HF phenotype in the near future.3,4 Although many HFpEF patients feel comfortable at rest, they frequently have profound limitations in exercise capacity, cardiac output reserve, and notably blunted heart rate response to exertion.
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Oraii et al. (2024) conducted an editorial in Heart failure with preserved ejection fraction (HFpEF). Rate-adaptive pacing was evaluated. Patients with heart failure with preserved ejection fraction frequently experience profound limitations in exercise capacity and a blunted heart rate response to exertion.
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