Key result
High initial systolic blood pressure in dogs with chronic renal failure was associated with increased risk of uremic crisis and death, with retinopathy or encephalopathy in 3 of 14 dogs with SBP ≥180 mm Hg.
Why the study?
Does high initial systolic blood pressure increase the risk of uremic crisis or death in dogs with chronic renal failure?
Population
45 dogs with spontaneous chronic renal failure
Comparison
High initial systolic blood pressure (SBP) vs Intermediate or low initial SBP
Design
Cohort
Authors
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High SBP signals higher uremic risk in canine CRF; hypothesis-generating for interventional trials.
Cohort (n=45)
Does high initial systolic blood pressure increase the risk of uremic crisis or death in dogs with chronic renal failure?
In dogs with chronic renal failure, high initial systolic blood pressure is associated with an increased risk of uremic crisis, death, and a greater decline in renal function.
Jacob et al. (2003) conducted a cohort in chronic renal failure (n=45). High initial systolic blood pressure vs. Intermediate or low systolic blood pressure was evaluated on uremic crisis, death, or decline in renal function. High initial systolic blood pressure in dogs with chronic renal failure was associated with increased risk of uremic crisis and death, with retinopathy or encephalopathy in 3 of 14 dogs with SBP ≥180 mm Hg.
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