Key result
Opioid-reduced anesthesia during adolescent idiopathic scoliosis surgery decreased day 1 morphine consumption compared to opioid-based anesthesia (0.8 vs 1.1 mg/kg; p=0.02).
Why the study?
Opioid-reduced anesthesia was suggested to decrease morphine consumption and chronic pain incidence after adolescent idiopathic scoliosis surgery.
Does opioid-reduced anesthesia reduce morphine consumption at day 1 in children undergoing adolescent idiopathic scoliosis surgery?
Cohort (n=69)
Does opioid-reduced anesthesia reduce morphine consumption at day 1 in children undergoing adolescent idiopathic scoliosis surgery?
Absolute Event Rate: 0.8% vs 1.1%
p-value: p=0.02
Opioid-reduced anesthesia during adolescent idiopathic scoliosis surgery significantly reduces postoperative morphine consumption and persistent neuropathic pain at 1 year.
ORA may reduce day-1 morphine after AIS surgery; hypothesis-generating and requires RCTs before practice change.
Aims: Opioid-reduced anesthesia (ORA) was suggested to decrease morphine consumption after adolescent idiopathic scoliosis (AIS) surgery and incidence of chronic pain. Materials & methods: A prospective analysis using the ORA in AIS surgery was performed. Two cohorts were compared: a control group (opioid-based anesthesia) and the ORA group. The main outcome was morphine consumption at day 1. Results: 33 patients operated for AIS using ORA were compared with 36 with opioid-based anesthesia. Morphine consumption was decreased in the ORA group (1.1 mg.kg-1 [0.2–2] vs 0.8 mg.kg-1 [0.3–2]; p = 0.02) at day 1. Persistent neuropathic pain at 1 year was decreased in the ORA group (p = 0.02). Conclusion: The ORA protocol is efficient to reduce postoperative morphine consumption in AIS surgery and preventing neuropathic pain.
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Julien‐Marsollier et al. (2021) conducted a cohort in Adolescent idiopathic scoliosis (n=69). Opioid-reduced anesthesia vs. Opioid-based anesthesia was evaluated on Morphine consumption at day 1 (p=0.02). Opioid-reduced anesthesia during adolescent idiopathic scoliosis surgery decreased day 1 morphine consumption compared to opioid-based anesthesia (0.8 vs 1.1 mg/kg; p=0.02).
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