Why the study?
Does RT-PCR and sequence analysis improve the detection and typing of human astroviruses compared to EIA in children with diarrhea?
Population
214 children (<18 months old) prospectively monitored for diarrhea in a periurban community of Mexico City
Comparison
RT-PCR and sequence analysis vs EIA (Enzyme Immunoassay)
Design
Cohort
Authors
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RT-PCR may improve HAstV detection and typing in pediatric diarrhea; leaves open whether it should replace EIA in routine practice.
Does RT-PCR and sequence analysis improve the detection and typing of human astroviruses compared to EIA in children with diarrhea?
RT-PCR and sequence analysis provide more sensitive detection and detailed epidemiological typing of human astroviruses than EIA.
Walter et al. (2001) studied this question.
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