June 1, 1982AnaesthesiaOpen Access

Diazepam and suxamethonium muscle pain (a dose‐response study)

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Why the study?

Does intravenous diazepam pretreatment reduce postoperative muscle pain in patients receiving suxamethonium?

Population

Patients receiving suxamethonium

Comparison

Diazepam intravenously 5 minutes prior to… vs No diazepam before suxamethonium

Follow-up

postoperative

Authors

RVR. S. Verma

Discussion

Member takes

Implication

May reduce suxamethonium-induced myalgia; hypothesis-generating and requires randomized confirmation before practice change.

Structured PICO

Does intravenous diazepam pretreatment reduce postoperative muscle pain in patients receiving suxamethonium?

Population

Patients receiving suxamethonium

Intervention

Diazepam intravenously (5 mg, 10 mg, 15 mg, or 20 mg) 5 minutes prior to suxamethonium

Comparator

No diazepam before suxamethonium

Outcome

Incidence of postoperative muscle painpatient reported

Intravenous diazepam pretreatment at doses of 10 mg or higher significantly reduces the incidence and severity of suxamethonium-induced postoperative muscle pain.

Cite This Study

R. S. Verma (1982) studied this question.

synapsesocial.com/papers/6a95200ea9fda6dc960f4016 https://doi.org/10.1111/j.1365-2044.1982.tb01284.x

View Full Paper

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Diazepam and suxamethonium muscle pain (a dose‐response study)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Diazepam and suxamethonium muscle pain (a dose‐response study)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider