Why the study?
Does induction with propofol compared to midazolam affect the QTc interval following suxamethonium and intubation in surgical patients?
Population
30 patients, ASA I or II, without cardiovascular disease, electrolyte abnormalities or receiving any…
Comparison
Propofol 1 mg kg-1 i.v. bolus followed by a… vs Midazolam 0.4 mg kg-1 i.v. bolus, then…
Design
Cohort
Follow-up
Up to 1 minute after tracheal intubation
Authors
Loading...
QTc monitoring during intubation remains prudent irrespective of induction agent; Level 3 data leaves open causal roles of suxamethonium versus laryngoscopy.
Does induction with propofol compared to midazolam affect the QTc interval following suxamethonium and intubation in surgical patients?
Induction with midazolam or propofol does not significantly affect the QTc interval, but subsequent suxamethonium administration and tracheal intubation cause QTc prolongation.
Michaloudis et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: