Urinary conditions with a distinctive clinical picture are not uncommon in newborn infants. The majority of infants show excellent response to treatment and early diagnosis is of great importance. In any circumstances it is difficult to obtain specimens of urine from these small subjects and the difficulties are frequently increased as a result of the anuria which is a common accompaniment of urinary disorders in its early stages. Usually the characteristic clinical features of these cases allow of a diagnosis being made and treatment being begun before examination of the urine has been possible.
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W. S. Craig (1935) studied this question.