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It is a matter of significant concern, that the articles which refer MDA-MB-435 cell line as a breast cancer cell line are still being published in peer reviewed journals of international repute, even in 2014. Questions have been raised, for the last 14 years or so, about its origin and caution has been advised against using the cell line as a model for breast cancer. 1 – 5 The origin of the cell line, notwithstanding few contradictory reports, 6 – 8 has been established to be of melanoma.
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Prasad et al. (2015) studied this question.
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