Why the study?
Does P-selectin blockade or gene deletion improve early pulmonary protection after lung ischemia or transplantation in animal models?
Does P-selectin blockade or gene deletion improve early pulmonary protection after lung ischemia or transplantation in animal models?
P-selectin blockade or genetic deletion confers early pulmonary protection and improves survival after lung ischemia or transplantation in animal models.
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Animal data support P-selectin targeting in lung ischemia; human translation remains untested and should not change practice.
Naka et al. (1997) studied this question.
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