Why the study?
To develop an algorithm for differential diagnostics and prediction of effective treatment in patients with short stature and preserved somatotropic function.
Does the IGF-1 generation test improve the differential diagnosis of short stature in children with preserved somatotropic function?
Does the IGF-1 generation test improve the differential diagnosis of short stature in children with preserved somatotropic function?
The IGF-1 generation test is highly effective for the differential diagnosis of short stature with preserved somatotropic function and for predicting response to recombinant GH treatment.
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Algorithm for short stature diagnosis needs prospective validation; leaves open routine clinical adoption.
Bolshova et al. (2020) studied this question.
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