Why the study?
More than one MitraClip may be implanted if a single device does not reduce MR adequately, but the clinical outlook across one, two, or multiple clips needed appraisal.
Does the implantation of multiple MitraClips compared to a single MitraClip affect the risk of cardiac death or heart failure rehospitalization in patients undergoing transcatheter mitral valve repair?
Does the implantation of multiple MitraClips compared to a single MitraClip affect the risk of cardiac death or heart failure rehospitalization in patients undergoing transcatheter mitral valve repair?
While implantation of one or two MitraClips yields favorable outcomes, the need for three or more clips as a bail-out strategy is associated with a worse long-term prognosis.
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Multiple MitraClip use warrants procedural caution; leaves open whether ≥3 clips independently worsen outcomes in observational data.
A 2021 study studied this question.
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