Real-World Experience of MitraClip for Treatment of Severe Mitral Regurgitation
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Why the study?
Does MitraClip implantation reduce mitral regurgitation severity and improve symptoms in high-surgical-risk patients with severe mitral regurgitation?
Population
27 patients with symptomatic severe chronic mitral regurgitation and high operative risk, mean age 74±12…
Design
Cohort
Follow-up
1 year (mean 332±140 days)
Authors
Discussion
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Implication
Supports MitraClip feasibility in high-surgical-risk severe MR; leaves open need for RCTs to confirm benefit over alternatives.
Structured PICO
Does MitraClip implantation reduce mitral regurgitation severity and improve symptoms in high-surgical-risk patients with severe mitral regurgitation?
P
Population
27 patients with symptomatic severe chronic mitral regurgitation (grade 3+ or 4+) and high operative risk (Logistic EuroSCORE ≥20% and STS-PROM ≥10% or specific surgical risk factors), mean age 74±12 years, 17 male, 56% degenerative and 44% functional MR.
I
Intervention
Percutaneous edge-to-edge mitral valve repair with the MitraClip system under fluoroscopic and 3D-TEE guidance.
O
Outcome
Procedural success, defined as successful and stable MitraClip placement with residual MR ≤2+ upon discharge.surrogate
MitraClip implantation is a safe and effective treatment for reducing mitral regurgitation and improving symptoms in high-surgical-risk patients, though a compromise between MR reduction and avoiding mitral stenosis is often required, particularly in functional MR.
Limitations
- relatively small number of recruited patients
Cite This Study
Chan et al. (2012) studied this question.
Topics
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