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INTRODUCTION 543 EVIDENCE THAT CHROMIUM (Cr) IS ESSENTIAL 544 Early Studies 544 Documentation of Human Cr Deficiency 545 Role of Cr in Lipid Metabolism ...... 547 Supplementation Trials 548 Cr Deficiency as a Factor in Other Conditions 55l MEASUREMENT OF Cr IN THE BODy. . . . . . . . . . . . . . . . . . . ... . . . . . . . . . . . . . . . ..... . . . . . . . . . . . . . 55l Cr in Blood . 552 Cr in Urine . ... . ..... .. .. . .... . 552 Cr in Hair 553 Current and Future Capabilities 554 Cr METABOLISM AND FUNCTION. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554 Absorption of Dietary Cr 555 Cr Transport 555 Identification of Metabolically Active Molecules 556 Other Metabolic Functions 557 IS Cr MARGINAL OR INADEQUATE IN THE DIETS OF SOME PEOPLE? ... ..... 557
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Offenbacher et al. (1988) studied this question.
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