Why the study?
Does 23Na MR imaging detect increased absolute tissue sodium concentration in human myocardial infarctions compared to normal tissue?
Population
20 patients with a history of prior myocardial infarction, left ventricular ejection fraction <= 35%, and…
Comparison
Sodium 23 magnetic resonance imaging to measure… vs Noninfarcted left ventricular regions, adjacent…
Design
Cohort
Authors
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23Na MR may detect MI sodium elevation; hypothesis-generating, should not yet change practice.
Does 23Na MR imaging detect increased absolute tissue sodium concentration in human myocardial infarctions compared to normal tissue?
Absolute tissue sodium concentration is significantly elevated in human myocardial infarction as measured by 23Na MR imaging, though it does not correlate with infarct age, size, or arrhythmia inducibility.
Ouwerkerk et al. (2008) studied this question.
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