Why the study?
The study was conducted to clinically evaluate whether coronary heart disease in the local population is caused by obesity.
Are obesity-associated factors such as BMI, blood pressure, and lipid profile significantly altered in patients with coronary heart disease compared to normal individuals?
Are obesity-associated factors such as BMI, blood pressure, and lipid profile significantly altered in patients with coronary heart disease compared to normal individuals?
Patients with coronary heart disease exhibit significantly higher BMI, blood pressure, and atherogenic lipid profiles compared to healthy controls, reinforcing the link between obesity-related factors and CHD.
Supports local obesity-CHD association; leaves open causal inference and need for larger studies.
Objective: The main objective of this study was to check clinically that Coronary Heart Disease in our local population caused by obesity. Study design: It is a comparative clinical study. Place and duration: Current clinical study was conducted in Lahore Medical & Dental College Lahore, Pakistan from December 2021to March 2022. Methodology: In Group X, 25 normal individuals were selected while in Group Y, 75 patients with Coronary Heart Disease were considered respectively. Intensity of Shoulder or arm pain, Shortness of breath, lipid profile, BMI, oxygen saturation, systolic and diastolic blood pressure and electrocardiogram (ECG). Lipid profile were performed through blood sample, Oxygen saturation levels were measured through oximeter, blood pressure with sphygmomanometer. The bio-statistically model SPSS was applied for the presentation of collected raw data. Results: Different parameters such as BMI, systolic and diastolic blood pressure, Intensity of Shoulder or arm pain, oxygen saturation, blood serum cholesterol, blood serum triglycerides, blood serum LDL, blood serum HDL levels and electrocardiogram (ECG) were measured comparatively in current study. The levels of these variables in Group-X and Group-Y were (18.02±01.02, 118.1±01.01, 72.01±0.01, 0.01±0.01, 99.0±0.03, 198.01±0.04, 138.02±0.02, 125.01±0.03, 45.01±0.01), (28.01±01.04, 178.0±01.03, 96.01±09.04, 90.01±0.02, 94.0±0.03, 268.01±0.01, 208.01±0.04, 185.01±0.01, 35.01±0.04) measured respectively. Conclusion: In present study different parameters such as BMI, systolic and diastolic blood pressure, Intensity of Shoulder or arm pain, oxygen saturation, blood serum cholesterol, blood serum triglycerides, blood serum LDL, blood serum HDL levels and electrocardiogram (ECG) were measured in both Group-X and Group-Y and a significant (P≤0.05) changes were observed in individuals of Group-Y than the Group-X comparatively.
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Tariq et al. (2022) studied this question.
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