Key result
High body mass index did not show any significant relationship with the severity of coronary artery disease in patients undergoing coronary angiography.
Why the study?
Uncertainty persists about the association between high BMI (overweight or obese) and coronary artery disease.
Does high BMI associate with increased severity of coronary artery disease in patients undergoing coronary angiography?
Cross-Sectional (n=478)
No
Does high BMI associate with increased severity of coronary artery disease in patients undergoing coronary angiography?
In a Pakistani cohort undergoing coronary angiography, higher BMI was not associated with increased angiographic severity of coronary artery disease.
Answers are grounded in this paper and cite their sources.
No BMI-CAD severity association on angiography observed; hypothesis-generating and should not yet change risk stratification.
Objectives: To establish or refute any association between high Body Mass Index (BMI) and Coronary Artery Disease in South Punjab area of Pakistan. Background: Ischemic heart disease has a strong relation with high Body Mass Index (BMI). But still uncertainty persists about the association that exists between overweight (BMI 25-29.9 kg/m2) or obese patients (BMI >30 kg/m2). Design: Observational, Cross Sectional Study. Setting: Cardiac cath lab department of Multan Institute of cardiology Multan. Duration of Study: Six month tenure extending between January 2017 to June 2017. Methods: The study was conducted in cardiac cath lab department of Multan Institute of cardiology, Multan. Total of Four hundred and seventy eight patients (478) over a period of two months were included in the study. All patients were having a coronary angiography due to a medical indication. Their BMI was calculated by using standard formula. Results: Out of 478 patients 335 (70.1%) patients were having optimal weight. 123 (25.7%) were overweight, 12 (2.5%) were mildly obese, 8 (1.7%) were severely obese patients. Optimal weight patients had 12.5% normal coronary angiogram, 26.3 % had single vessel CAD, 20% had two vessel disease and 41.2% had severe triple vessel disease. Over weight patients had 17.9% normal coronary angiograms, single vessel CAD was seen in 26.8% patients, 21.9% patients had two vessel disease and 33.3% had severe triple vessel CAD. Mildly obese patients had 8.3% normal coronary angiograms, 50% had single vessel CAD, 25% had two vessel disease, and 16.7% had severe Triple vessel disease. Among severe obese patients 12.5% had normal coronary angiography, 25% had single vessel disease, 50% had two vessel disease, and 12.5% had severe triple vessel disease. Conclusion: Patients undergoing Coronary Angiogram in the region of south Punjab did not show any significant relationship between severity of CAD (Severe two vessels & severe Triple vessel disease) and BMI.
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Farid et al. (2019) conducted a cross-sectional in Coronary Artery Disease (n=478). High Body Mass Index vs. Optimal weight (BMI < 25 kg/m2) was evaluated on Severity of Coronary Artery Disease (Severe two vessel and triple vessel disease). High body mass index did not show any significant relationship with the severity of coronary artery disease in patients undergoing coronary angiography.
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