Why the study?
Cardiac intimal sarcoma is extremely rare and aggressive, presenting risks of misdiagnosis as myxoma and raising the hypothetical concept of malignant transformation.
Highlights the risk of misdiagnosing aggressive cardiac intimal sarcomas as benign myxomas and the need for careful histopathological evaluation and follow-up.
Recurrent atrial masses after presumed myxoma resection warrant sarcoma consideration; leaves open optimal adjuvant strategies for intimal sarcoma.
Cardiac intimal sarcoma is extremely rare and aggressive primary malignant cardiac tumors. Here, we reported the case of a young man initially operated for a tumor of the left atrium, causing a dynamic obstruction of the mitral valve and (mis-)diagnosed as a myxoma at the histopathological analysis. Patient presented a local recurrence at 3 months and was reoperated. Pathology revealed this time the presence of an intimal sarcoma. Patient received adjuvant chemotherapy. Despite a good local control, the 1-year follow-up positron emission tomography scan revealed the presence of a metastasis in the left adrenal gland that was surgically resected. This article aims to highlight the risk of misdiagnosis in case of cardiac tumors, the hypothetical concept of malignant transformation of a cardiac myxoma, the aggressive course of the extremely rare cardiac intimal sarcoma, and the therapeutic modalities available to treat this pathology.
No takes yet. Share an insight, caveat, or question.
Durieux et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: