Early Right Ventricular Response To Cardiac Resynchronization Therapy: Impact on Clinical Outcomes
Why the study?
Does early normalization of right ventricular function after CRT implantation improve long-term outcomes in heart failure patients?
Population
194 heart failure patients who successfully underwent cardiac resynchronization therapy device implantation…
Design
Cohort
Authors
Discussion
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Implication
May inform post-CRT risk stratification in HF; hypothesis-generating for RV recovery as a modifiable target.
Structured PICO
Does early normalization of right ventricular function after CRT implantation improve long-term outcomes in heart failure patients?
P
Population
194 heart failure patients who successfully underwent cardiac resynchronization therapy (CRT) device implantation from January 2005 to January 2014, with available pre- and post-procedural right ventricular function (RVF) assessment.
I
Intervention
Cardiac resynchronization therapy (CRT) device implantation
O
Outcome
Composite of all-cause mortality and urgent heart transplantationcomposite
Acute normalization of right ventricular function after CRT implantation is an independent predictor of transplant-free survival in heart failure patients.
Cite This Study
Stolfo et al. (2015) studied this question.