subclinical) is most often treated with intrauterine infusion of a specific formulation of cephapirin (Metricure, Merk) which has beneficial effects on clinical cure and subsequent reproductive performance Although prostaglandins are still used for treatment and prevention of endometritis, there is no evidence of efficacy neither for improving reproductive efficiency nor for reducing its incidence [2], Lefebvre and Stock 2012). However, this hormone is essential in synchronization protocols for controlled breeding programs. The aim of the present article is to review non-antibiotic approaches used to treat or prevent PUDs in dairy cows.
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