Key result
Appropriate chemotherapy led to almost total resolution of an extensive cardiac large-cell lymphoma presenting as right-sided heart failure at 6-month follow-up.
Case Report (n=1)
No
Cardiac large-cell lymphoma can present as right-sided heart failure and may show near-total resolution with appropriate chemotherapy.
Cardiac lymphoma merits consideration in right heart failure differentials; extends sparse case reports but leaves open prospective validation.
A 57-year-old man with a history of coronary artery disease and chronic obstructive pulmonary disease was admitted to another hospital with progressive dyspnea, ascites, edema, and mild jaundice. He was transferred to St. Luke's Episcopal Hospital for further evaluation. Biplane transesophageal echocardiography (TEE) revealed an extensive tumor mass in the right atrium and left atrium (Fig TEE-guided biopsy of the superior vena cava mass revealed histology of large-cell lymphoma (B-cell type). At 6-month follow-up, after appropriate chemotherapy, repeat TEE showed almost total resolution of the tumor bulk, with only a small residual mass seen in the right atrium (Fig 1
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Gaos et al. (1993) conducted a case report in Right-sided heart failure secondary to cardiac large-cell lymphoma (n=1). Chemotherapy was evaluated on Tumor resolution. Appropriate chemotherapy led to almost total resolution of an extensive cardiac large-cell lymphoma presenting as right-sided heart failure at 6-month follow-up.
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