Key result
Health care-associated infective endocarditis was an independent predictor of in-hospital mortality compared with community-acquired cases (45.8% vs 22.0%; OR 2.83; 95% CI 1.34-5.98; P=0.007).
Why the study?
Does health care-associated infective endocarditis increase mortality compared to community-acquired endocarditis?
Population
292 episodes of infective endocarditis, including 83 episodes of health care-associated infective…
Comparison
Health care-associated infective endocarditis vs Community-acquired endocarditis
Design
Cohort
Follow-up
1 year
Authors
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May inform prognosis in health care-associated cases; leaves open whether targeted prevention improves outcomes.
Cohort (n=292)
Does health care-associated infective endocarditis increase mortality compared to community-acquired endocarditis?
Odds Ratio: 2.83 (95% CI 1.34–5.98)
Absolute Event Rate: 45.8% vs 22%
p-value: p=0.007
Health care-associated infective endocarditis accounts for a significant proportion of endocarditis cases and is independently associated with higher in-hospital and 1-year mortality compared to community-acquired cases.
Fernández‐Hidalgo et al. (2008) conducted a cohort in Infective endocarditis (n=292). Health care-associated infective endocarditis vs. Community-acquired endocarditis was evaluated on In-hospital mortality (OR 2.83, 95% CI 1.34-5.98, p=0.007). Health care-associated infective endocarditis was an independent predictor of in-hospital mortality compared with community-acquired cases (45.8% vs 22.0%; OR 2.83; 95% CI 1.34-5.98; P=0.007).
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