Why the study?
Does the choice of bioprosthetic valve or homograft compared to mechanical prosthesis affect 5-year mortality in patients with active aortic valve infective endocarditis?
Population
167 patients with definite acute aortic valve infective endocarditis who underwent aortic replacement
Comparison
Bioprosthetic valve (heterograft) or homograft vs Mechanical prosthesis
Design
Cohort
Follow-up
5 years
Authors
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May support mechanical prosthesis preference in younger aortic endocarditis patients; leaves open randomized confirmation of survival differences.
Does the choice of bioprosthetic valve or homograft compared to mechanical prosthesis affect 5-year mortality in patients with active aortic valve infective endocarditis?
In patients with acute aortic valve infective endocarditis, the use of bioprosthetic valves may be associated with lower 5-year survival compared to mechanical valves, particularly in patients aged 65 years or younger.
Nguyen et al. (2009) studied this question.